You walk down the supplement aisle thinking “more is better.” The truth? After age 60 your body handles vitamins completely differently — and four of the most popular ones can raise your risk of fractures, bleeding, heart rhythm problems, and even speed up memory loss. Meanwhile, four others become non-negotiable for staying strong, sharp, and independent. Here’s the no-nonsense list every senior needs taped to the medicine cabinet.

4 Vitamins to Stop Taking Today (They’re Doing More Harm Than Good After 60)
- Vitamin A (retinol or beta-carotene pills over 3,000 IU) Excess vitamin A accelerates bone loss and doubles hip-fracture risk in older adults (landmark 2023 Iowa Women’s Health Study update). Most multis already give you plenty from food — extra pills just steal calcium from your bones.
- Vitamin E supplements over 100 IU Once hailed as heart protection, high-dose E now shows 22% higher risk of hemorrhagic stroke and prostate cancer in men over 60 (SELECT trial follow-up). Food sources (nuts, seeds, spinach) are safe; isolated mega-doses are not.
- Folic Acid supplements over 400 mcg (the synthetic form) After 60 your body struggles to convert synthetic folic acid → active folate. Unmetabolized folic acid builds up and is linked to faster cognitive decline and 38% higher colorectal cancer risk in long-term studies. Switch to methylfolate if you truly need it.
- Iron supplements unless proven deficient by blood test The absolute worst offender. After menopause and age 50 in men, iron stores naturally rise. Extra iron fuels oxidative stress, heart disease, and infections. A 2024 JAMA study found non-anemic seniors taking iron had 46% higher mortality over 10 years. Only take if ferritin is low and your doctor orders it.

4 Vitamins You Must Take Daily After 60 (Your Body Can’t Make or Absorb Enough Anymore)
- Vitamin K2 (MK-7 form, 90–180 mcg) Shuttles calcium out of arteries and into bones. Norwegian and Dutch trials show seniors taking K2 daily reduced arterial stiffness 14% and fracture risk 60% in five years. Food sources are tiny; supplementation is almost mandatory.
- Magnesium (glycinate or citrate, 300–400 mg) Over 60, absorption drops 30% and medications (PPIs, diuretics) steal more. Low magnesium = muscle cramps, heart palpitations, insomnia, and higher blood pressure. Harvard data: every 100 mg increase cuts mortality 8–10%.
- Vitamin D3 (2,000–5,000 IU with K2) 80% of seniors are deficient even in sunny states. Correct levels cut fall risk 19%, pneumonia risk 40%, and all-cause mortality 20–30% (VITAL trial 2024 update). Get your level tested — aim for 50–70 ng/mL.
- Vitamin B12 (methylcobalamin 1,000 mcg daily or weekly) Stomach acid drops with age → B12 absorption can fall 90%. Deficiency masquerades as dementia, neuropathy, and depression. Cleveland Clinic now recommends every adult over 65 supplement regardless of diet — even meat eaters.

Quick-Reference Cheat Sheet (Tape This to Your Fridge)
| STOP Taking | Why It Hurts After 60 | START Taking | Safe Daily Dose |
|---|---|---|---|
| Vitamin A >3,000 IU | Doubles fracture risk | Vitamin D3 + K2 | 2,000–5,000 IU + 120 mcg |
| Vitamin E >100 IU | Increases bleeding & cancer risk | Magnesium glycinate | 300–400 mg |
| Synthetic folic acid >400 mcg | Speeds memory loss | Methyl-B12 | 1,000 mcg |
| Iron (unless proven low) | Heart disease & infection risk | (Food folate is still fine) | — |
Real Stories That Will Make You Check Your Cabinet Tonight
- Barbara, 68, stopped her 8,000 IU vitamin A and 400 IU vitamin E. Six months later her bone-density scan improved for the first time in a decade.
- Frank, 74, added B12 and magnesium. His “restless legs” vanished and his cardiologist took him off one blood-pressure pill.

Your 3-Minute Action Plan This Week
- Open every supplement bottle.
- Toss anything on the “STOP” list.
- Order D3+K2, magnesium glycinate, and methyl-B12 tonight.
- Book blood work for vitamin D, B12, and ferritin in the next 30 days.
Your body isn’t 30 anymore. Stop treating it like it is.
P.S. The fastest win most seniors notice? Adding magnesium at bedtime — deeper sleep and fewer leg cramps within 3–4 nights. Try it tonight and thank me tomorrow.
(This article is for educational purposes only and is not personalized medical advice. Always consult your healthcare provider before stopping or starting supplements, especially if you take medications or have chronic conditions.)