Pests are more than just an inconvenience—they can disrupt your home and peace of mind. The U.S. Census Bureau reports nearly 14 million American households encounter rodents annually, while cockroaches thrive in warm, humid environments, and lizards are a common nuisance in tropical regions.

Chemical sprays and pest control services are the usual go-to solutions, but many homeowners search for affordable, natural alternatives. That’s why a surprising online trend has gained attention: using toothpaste as a pest repellent.
But does this everyday bathroom essential actually keep mice, cockroaches, or lizards away—or is it just another internet myth? Let’s explore what science, household experiments, and cultural traditions reveal about this unusual hack.
Why Toothpaste Might Work Against Pests
Toothpaste contains several compounds that can make it unappealing to unwanted intruders:
- Menthol and peppermint oil: Found in mint toothpastes, these odors overwhelm rodents and insects.
- Fluoride and detergents: Create surfaces that pests dislike walking across.
- Sticky texture: Forms a mild barrier in cracks, corners, or drains.
While not backed by extensive scientific studies, anecdotal reports suggest toothpaste can act as a short-term deterrent, especially when combined with good hygiene and sealing entry points.

Can Toothpaste Repel Mice?
Mice rely heavily on their sense of smell to locate food. Strong scents like peppermint can overwhelm them and disrupt their pathways.
How homeowners use it:
- Smear mint toothpaste along baseboards, under doors, or around small holes.
- Mix toothpaste with peppermint essential oil, apply on cotton balls, and place near entry points.
Limitations:
Mice are persistent and may return once the odor fades. Toothpaste works best as a supporting tactic alongside traps and sealing gaps.
Can Toothpaste Repel Cockroaches?
Cockroaches are highly adaptable, but they dislike strong, chemical-like odors.
What works:
- Apply thin layers of toothpaste around drains, corners, or behind appliances.
- Use as a temporary barrier in cracks where roaches enter.
Case in point: A Florida homeowner reported fewer roaches overnight after applying toothpaste in sink drains. However, the effect faded within days, showing it’s temporary at best.
Can Toothpaste Repel Lizards?
Lizards aren’t harmful but often make people uncomfortable indoors. They avoid sticky surfaces and dislike menthol’s cooling effect.
Practical uses:
- Apply toothpaste along windowsills and wall cracks.
- Place near light fixtures where insects (and lizards) gather.
Reports from tropical households note lizards avoided toothpaste-treated areas for several days, suggesting it can provide short-term relief.

Pros and Cons of Using Toothpaste as Pest Control
| Aspect | Advantage | Limitation |
|---|---|---|
| Cost | Cheap, already in your home | Needs frequent reapplication |
| Safety | Safer than chemical sprays | Risk if ingested by kids or pets |
| Effectiveness | Works in small areas | Weak against major infestations |
| Convenience | Easy to smear in cracks or drains | Can stain, messy to clean up |
Natural Alternatives That Work Better
If you want longer-lasting natural pest control, try these proven remedies:
- Peppermint oil spray – Effective against both mice and roaches.
- Bay leaves – Place in cupboards to discourage cockroaches.
- Garlic or onion – Strong odor repels lizards in many cultures.
- Citrus peels – Fresh lemon or orange peels deter insects.
Used together with regular cleaning and sealing, these create a stronger defense than toothpaste alone.

Final Thoughts
Toothpaste as a pest repellent is an unusual but intriguing hack. It can repel mice, cockroaches, and lizards for a short time, especially in small, targeted areas. But it’s not a long-term or standalone solution. For persistent infestations, combine it with natural remedies, good hygiene, and professional pest control if needed.
FAQs
Does toothpaste kill pests?
No. It only repels temporarily due to its smell and texture.
Which toothpaste works best?
Mint or peppermint-based toothpastes are more effective than fruity flavors.
Is it safe to use around pets and kids?
Generally safe in small amounts, but avoid leaving large smears where they could ingest it.
Can I rely only on toothpaste for pest control?
No. It should complement other strategies, not replace them.
Disclaimer: This article is for informational purposes only and does not replace professional pest-control advice. For serious infestations, consult a licensed expert.